Tadapox Tablet contains two active ingredients: Tadalafil and Dapoxetine. It is used to treat two common male sexual health issues: erectile dysfunction (ED) and premature ejaculation (PE). There are certain medications that should not be taken with Tadapox due to potential interactions that can result in adverse effects or reduced efficacy. Here’s why: Tadalafil Interactions: Nitrates: Drugs such as nitroglycerin, isosorbide mononitrate, and isosorbide dinitrate, commonly used to treat angina (chest pain) and other heart conditions, can interact dangerously with Tadalafil. Combining Tadalafil with nitrates can cause a severe drop in blood pressure, leading to dizziness, fainting, or even a heart attack. Therefore, Tadalafil should not be used in combination with nitrates. Alpha-Blockers: Medications used to treat high blood pressure (hypertension) or benign prostatic hyperplasia (BPH) such as doxazosin, terazosin, and Tadapox Tablet , can also interact with Tadalafil. Combining Tadalafil with alpha-blockers can lead to a significant drop in blood pressure, causing symptoms like dizziness, lightheadedness, fainting, and in rare cases, heart attack or stroke. Dapoxetine Interactions: Serotonergic Medications: Dapoxetine, being a selective serotonin reuptake inhibitor (SSRI), can interact with other serotonergic medications, such as antidepressants like SSRIs, SNRIs, or MAOIs, as well as certain migraine medications and opioid analgesics. Combining Dapoxetine with these medications can increase the risk of serotonin syndrome, a potentially life-threatening condition characterized by symptoms such as confusion, hallucinations, rapid heart rate, high blood pressure, fever, excessive sweating, shivering, tremor, muscle stiffness, twitching, loss of coordination, nausea, vomiting, and diarrhea. Reasons to Avoid Combining Tadapox with Certain Medications: Hypotension (Low Blood Pressure): Combining Tadapox with medications such as nitrates or alpha-blockers can lead to a significant drop in blood pressure, potentially causing dizziness, fainting, or even more serious cardiovascular complications. Serotonin Syndrome: Combining Tadapox with serotonergic medications can increase the risk of serotonin syndrome, a potentially life-threatening condition characterized by a combination of symptoms affecting the body’s mental status, neuromuscular system, and autonomic nervous system. Precautions: Always inform your healthcare provider about all the medications you are currently taking, including prescription, over-the-counter, herbal supplements, and vitamins, before starting Tadapox or any other new medication. Follow your healthcare provider’s instructions carefully and never self-medicate or adjust your medication regimen without consulting them first. If you experience any concerning symptoms or side effects while taking Tadapox or any other medication, seek medical attention immediately.